Conference abstract2009Open access
Mast Cell Chymase Regulates Homeostatic Intestinal Barrier Function
Groschwitz, K.R.; Ahrens, R.; Osterfeld, H. et al.
Magnus Åbrink
Department of Animal Biosciences
Faculty of Veterinary Medicine and Animal Sciences
Email: magnus.abrink@slu.se
ORCID: 0000-0002-1335-3927
Publications
2009
Research article2009Peer reviewed
Reduction with dithiothreitol causes serglycin-specific defects in secretory granule integrity of bone marrow derived mast cells
Braga, Tiago; Ringvall, Maria; Tveit, Heidi et al.
Conference abstract2009Peer reviewed
A protective role of the murine chymase, mouse mast cell protease 4 (mMCP-4), in a model of allergic inflammation
Waern, Ida; Jonasson, Sofia; Hjoberg, Josephine et al.
Research article2009Peer reviewedOpen access
Mouse Mast Cell Protease 4 Is the Major Chymase in Murine Airways and Has a Protective Role in Allergic Airway Inflammation : Protective Role of Chymase in Asthma
Waern, Ida; Jonasson, Sofia; Hjoberg, Josephine et al.
Research article2009Peer reviewed
Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules
Niemann, Carsten U.; Cowland, Jack B.; Ralfkiaer, Elisabeth et al.
Research article2009Peer reviewedOpen access
Critical Role of Mast Cell Chymase in Mouse Abdominal Aortic Aneurysm Formation
Sun, Jiusong; Zhang, Jie; Lindholt, Jes S. et al.
Research article2009Peer reviewedOpen access
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism
Groschwitz, Katherine R.; Ahrens, Richard; Osterfeld, Heather et al.
Research article2009Peer reviewedOpen access
Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis
Magnusson Sofia E., Pejler Gunnar, Kleinau Sandra, Abrink Magnus.
Research article2009Peer reviewed
Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice
Wernersson, Sara; Braga, Tiago; Sawesi, Osama et al.
Review article2009Peer reviewed
Serglycin proteoglycan: regulating the storage and activities of hematopoietic proteases
Pejler, Gunnar; Abrink, Magnus; Wernersson, Sara.
2008
Conference abstract2008
Mouse Mast Cell Protease 4 has a detrimental role in anti-GBM-induced glomerulonephritis
Scandiuzzi, Lisa; Åbrink, Magnus; Daugas, Eric et al.
Conference abstract2008Open access
Delayed Contraction of the CD8+ T-cell Response Towards Lymphocytic Choriomeningitis Virus Infection in Mice Lacking Serglycin
Grujic, M.; Pravsgaard, Christensen J.; Abrink, M. et al.
Research article2008Peer reviewed
Generation and characterization of a Gdf1 conditional null allele
Bengtsson, Henrik; Epifantseva, Irina; Åbrink, Magnus et al.
Research article2008Peer reviewed
Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan
Ringvall, Maria; Roennberg, Elin; Wernersson, Sara et al.
Research article2008Peer reviewedOpen access
Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice
Woulfe, Donna S.; Lilliendahl, Joanne Klimas; August, Shelley et al.
Research article2008Peer reviewedOpen access
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis
Piliponsky Adrian M., Chen Ching-Cheng, Nishimura Toshihiko, Metz Martin, Rios Eon J., Dobner Paul R., Wada Etsuko, Wada Keiji, Zacharias Sherma, Mohanasundaram Uma M., Faix James D., Abrink Magnus, Pejler Gunnar, Pearl Ronald G., Tsai Mindy, Galli Stephen J..
Research article2008Peer reviewedOpen access
Delayed contraction of the CD8(+) T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin
Grujic Miriana, Christensen Jan P., Sorensen Maria R., Abrink Magnus, Pejler Gunnar, Thomsen Allan R..
2007
Research article2007Peer reviewedOpen access
Rab27b regulates number and secretion of platelet dense granules
Tolmachova, Tanya; Åbrink, Magnus; Futter, Clare E. et al.
Research article2007Peer reviewedOpen access
Bcl-2 and Bcl-XL are indispensable for the late phase of mast cell development from mouse embryonic stem cells
Möller, Christine; Karlberg, Mats; Åbrink, Magnus et al.
Research article2007Peer reviewedOpen access
Rab27b regulates mast cell granule dynamics and secretion
Mizuno, Kouichi; Tolmachova, Tanya; Ushakov, Dmitry S. et al.
Research article2007Peer reviewedOpen access
Serglycin proteoglycan is required for secretory granule integrity in mucosal mast cells
Braga T, Grujic M, Lukinius A, Hellman L, Abrink M, Pejler G.
Research article2007Peer reviewed
Mast cell proteases
Pejler G, Abrink M, Ringvall M, Wernersson S.
Research article2007Peer reviewedOpen access
Neutrophil elastase depends on serglycin proteoglycan for localization in granules
Niemann CU, Abrink M, Pejler G, Fischer RL, Christensen EI, Knight SD, Borregaard N.
2006
Conference abstract2006
Role of the chymase, mouse mast cell proteinase 4 in experimental Bullous Pemphigoid
Zhao, M.; Xu, W.; Abrink, M. et al.
Research article2006Peer reviewedOpen access
Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia
Tolmachova, Tanya; Åbrink, Magnus; Seabra, Miguel C..
Research article2006Peer reviewed
Mast cells can enhance resistance to snake and honeybee venoms
Metz M, Piliponsky AM, Chen CC, Lammel V, Abrink M, Pejler G, Tsai M, Galli SJ.
Research article2006Peer reviewedOpen access
Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide
Zernichow L, Abrink M, Hallgren J, Grujic M, Pejler G, Kolset SO.
Research article2006Peer reviewed
Mast cell-dependent activation of pro matrix metalloprotease 2: a role for serglycin proteoglycan-dependent mast cell proteases
Lundequist A, Abrink M, Pejler G.
Research article2006Peer reviewedOpen access
A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components
Henningsson F, Hergeth S, Cortelius R, Abrink M, Pejler G.
2005
Conference abstract2005
Neutrophil elastase, but not myeloperoxidase, depends on serglycin proteoglycan for granule localization in neutrophils
Niemann, C.U.; Åbrink, M.; Pejler, G. et al.
Research article2005Peer reviewedOpen access
A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
Tchougounova, Elena; Lundequist, Anders; Fajardo, Ignacio et al.
Research article2005Peer reviewedOpen access
Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage
Grujic M, Braga T, Lukinius A, Eloranta ML, Knight SD, Pejler G, Abrink M.
2004
Research article2004Peer reviewed
A novel Krüppel-Associated box identified in a panel of mammalian zinc finger proteins
Looman, Camilla; Hellman, Lars; Åbrink, Magnus.
Research article2004Peer reviewed
The 5 '-AMP-activated protein kinase gamma 3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle
Barnes BR, Marklund S, Steiler TL, Walter M, Hjalm G, Amarger V, Mahlapuu M, Leng Y, Johansson C, Galuska D, Lindgren K, Abrink M, Stapleton D, Zierath JR, Andersson L.
Research article2004Peer reviewed
Cooperation between Mast Cell Carboxypeptidase A and the Chymase Mouse Mast Cell Protease 4 in the Formation and Degradation of Angiotensin II*
Lundequist, Anders; Tchougounova, Elena; Åbrink, Magnus et al.
2003
Research article2003Peer reviewedOpen access
Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality
Li, Jin-Ping; Gong, Feng; Hagner-McWhirter, Åsa et al.
Research article2003Peer reviewedOpen access
The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover
Tchougounova E, Pejler G, Abrink M.
Research article2003Peer reviewed
MZF6D, a novel KRAB zinc-finger gene expressed exclusively in meiotic male germ cells
Looman C, Mark C, Abrink M, Hellman L.
2002
Research article2002Peer reviewedOpen access
KRAB zinc finger proteins: An analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution
Looman, Camilla; Åbrink, Magnus; Mark, Charlotta et al.
2001
Research article2001Peer reviewedOpen access
Conserved interaction between distinct Kruppel-associated box domains and the transcriptional intermediary factor 1 beta
Åbrink, Magnus; Ortiz, José A.; Mark, Charlotta et al.
Research article2001Peer reviewed
Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19
Mark, Charlotta; Looman, Camilla; Åbrink, Magnus et al.
2000
Research article2000Peer reviewedOpen access
Expression of lactoferrin in the kidney: Implications for innate immunity and iron metabolism
Åbrink, Magnus; Larsson, E.; Gobl, A. E. et al.
1999
Research article1999Peer reviewed
Comparative analysis of KRAB zinc finger proteins in rodents and man: Evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes
Mark, Charlotta; Åbrink, Magnus; Hellman, Lars.
1998
Research article1998Peer reviewed
Demethylation of ERV3, an endogenous retrovirus regulating the Kruppel-related zinc finger gene H-plk, in several human cell lines arrested during early monocyte development
Åbrink, Magnus; Larsson, Erik; Hellman, Lars.
1995
Research article1995Peer reviewed
Isolation of cDNA Clones for 42 Different Krüppel-Related Zinc Finger Proteins Expressed in the Human Monoblast Cell Line U-937
Åbrink, Magnus; Aveskogh, M.; Hellman, Lars.
1994
Research article1994Peer reviewed
Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage
Åbrink, Magnus; Gobl, A. E.; Huang, R. et al.
1993
Research article1993Peer reviewed
Expression of a Mast Cell Tryptase in the Human Monocytic Cell Lines U-937 and Mono Mac 6
Huang, R.; Åbrink, Magnus; Gobl, A. E. et al.
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